Cognitive behavioural therapy (CBT) for treatment resistant depression (TRD).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN81845520

Enrollment

Registered

2004-09-30

Start date

2004-01-01

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders: Depression Mental and Behavioural Disorders Depression

Interventions

1. Usual care 2. Usual care and CBT

Eligibility

Inclusion criteria

Inclusion criteria: Primary care based patients who have not responded to antidepressant medication given at an adequate dose for 6 weeks or longer.

Exclusion criteria

Exclusion criteria: Added July 2008: 1. Patients with bipolar disorder, psychosis, personality disorder or major alcohol or substance abuse problems 2. Patients who had been continually depressed for more than 5 years 3. Patients those unable to complete the study questionnaires 4. Patients who had previously or were currently receiving CBT therapy 5. Patients currently receiving other psychotherapy or secondary care for their depression

Design outcomes

Primary

Measure	Time frame
Beck Depression Inventory (BDI) score at 4 months post-randomisation.	—

Secondary

Measure	Time frame
Quality of Life	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026