Borderline Intellectual Functioning (BIF) Mental and Behavioural Disorders Borderline Intellectual Functioning (BIF)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 6 to 11 years old and attending primary mainstream school 2. Full Scale Intelligence Quotient score ranging from 71 to 85 determined with the WISC-III 3. Presence of learning disabilities assessed with the standardized test battery for developmental dyslexia and dysorthographia and dyscalculia 4. Difficulties in executive functions and or verbal comprehension assessed with Modified Barrage bell test;Tower of London (TOL) and the Test of Reception of Grammar (TROG2) 5. Presence of an impact on daily life of the above mentioned difficulties as measure by the Child Behavioral Checklist and Vineland2
Exclusion criteria
Exclusion criteria: 1. Presence of major neuropsychiatric disorders (such as ADHD and autism spectrum disorder) 2. Presence of neurological conditions:epilepsy; traumatic brain injury; brain malformations; infectious disease involving the central nervous system 3. Presence of systemic diseases such as diabetes or dysimmune disorders 4. Presence of genetic syndromes such as Down syndrome or Fragile X syndrome 5. Positive history for psychoactive drugs, particularly referring to current or past use of psychostimulants, neuroleptics, antidepressants, benzodiazepines and antiepileptic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All outcome measures are performed at two time points: within two months prior to the beginning of the treatment (T0) and within two months after the end of the treatment (T1). 1. Intellectual functioning is assessed with the Wechsler Intelligent Scale for Children-III (WISC-III) at T0 and T1 2. Movement skills is assessed with Movement Assessment Battery for Children (M-ABC) at T0 and T1 3. Emotional intelligence is assessed with the Emotional Quotient Inventory-Youth Version at T0 and T1 4. Child behavior is assessed with the Child Behaviour CheckList 6-18, CBCL and Vineland 2 at T0 and T1 | — |
Secondary
| Measure | Time frame |
|---|---|
| All outcome measures are performed at two time points: within two months prior to the beginning of the treatment (T0) and within two months after the end of the treatment (T1). 1. Executive function is assessed using the Modified Bells Test (to assess selective attention), the Tower of London test (to assess planning ability and inhibitory control) and the Neuropsychological Evaluation Battery for developmental age 5-11 (to assess speech fluency) at T0 and T1 2. Language comprehension is assessed using the Test of Reception of Grammar-2 (TROG2) at T0 and T1 3. Memory is assessed using selective word retrieval and visual memory is assessed with the Corsi Test using Neuropsychological Evaluation Battery for developmental (age 5-11) at T0 and T1 4. Modifications of brain function and morphology are evaluated with magnetic resonance imaging advanced techniques, such as diffusion tensor imaging (DTI), functional MRI (fMRI), resting state fMRI and high resolution volumetric acquisition at T0 and T1 | — |
Countries
Italy