A randomised trial of total prostatectomy versus radiotherapy versus no immediate treatment in early prostate cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN81687381

Enrollment

1800

Registered

2000-04-06

Start date

1994-06-01

Completion date

Unknown

Last updated

2017-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer Cancer Prostate

Interventions

1. The first group receives total prostatectomy 2. The second receive radiotherapy 3. The third receive no immediate treatment

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed, biopsy-proven adenocarcinoma of the prostate 2. Stage T1b/T1c/T2, N0, M0 3. Negative bone scan 4. No previous malignancy (except skin)

Exclusion criteria

Exclusion criteria: Opposite of inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. Survival time to metastases 2. Morbidity 3. Local recurrence 4. Quality of life 5. Time to progression	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Belgium, Switzerland, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026