Stroke Circulatory System Stroke, not specified as haemorrhage or infarction
Conditions
Interventions
40 participants with arm weakness are randomly allocated to two groups:
Intervention group: Patients will receive early (within the first 6 weeks after stroke) intensive training over
Sponsors
University of Manchester
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Acute stroke patients from Salford Royal Foundation Trust (SRFT) 2. Mild to moderate proximal upper limb weakness (MRC muscle scale 4 or less) 3. Able to reach at least 15cm while supported in the arm-trainer 4. Full upper limb function pre-morbidly
Exclusion criteria
Exclusion criteria: 1. Contraindications to transcranial magnetic stimulation (TMS), i.e. metal implants or epilepsy. 2. Previous stroke 3. Shoulder pain over 3/10 on visual analogue scale 4. Unable to give informed consent. 5. Severe neglect 6. Complete sensory loss 7. Suspected or confirmed pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor Evoked Potential to Transcranial Magnetic Stimulation Measures at baseline, 6 and 12 weeks after stroke. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Arm function measured by Motricity Index and Fugl-Meyer score at baseline, 6 and 12 weeks after stroke 2. Reaching accuracy is determined at baseline, 6 and 12 weeks after stroke 3. Feasibility of protocol measured by exit interview at 12 weeks after stroke | — |
Countries
England, United Kingdom
Contacts
Public ContactUlrike Hammerbeck
Outcome results
None listed