Tuberculosis Infections and Infestations Tuberculosis
Conditions
Interventions
Parent/patient/household based contact based screening will be used to investigate a newly-developed approach of:
1. Initiating contact screening at home by the patient themselves, wit
Sponsors
Malawi National Tuberculosis Programme (Malawi)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Pulmonary tuberculosis (PTB) patients registering at Queen Elizabeth Central Hospital (QECH), Malawi 2. Self-report of one or more under 5 year old household contact 3. Residence within Blantyre 4. Able and willing to provide written consent to participate in the study, including a 3 month household visit 5. If an inpatient: likely to be discharged within a two week period Contacts will be defined as members of the same household (defined as sharing meals) or other residents of the same dwelling who share physical space such as sleeping or living rooms. Participation by contacts will be through oral consent, using a patient information leaflet.
Exclusion criteria
Exclusion criteria: 1. Unable or unwilling to provide informed consent 2. Hospitalised patients who are unlikely to be discharged within a two week period (e.g due to retreatment requiring on TB treatment, and if transferred in and out of QECH) 3. Membership of a household that has already been recruited into the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The prevalence of bacteriologically confirmed TB in adult and child contacts diagnosed within three months of the diagnosis of the index case 2. The proportion of child contacts under 5 year who start IPT within three months of the diagnosis of the index case | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportions of contacts under 5 years old who initiate and complete 6 months of IPT | — |
Countries
Malawi
Outcome results
None listed