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Impact of graded nursing interventions based on quantitative risk assessment on psychological stress responses in patients undergoing resection for primary liver cancer

The impact of graded nursing interventions based on quantitative risk assessment on psychological stress responses in patients undergoing resection for primary liver cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN81587743
Enrollment
80
Registered
2025-04-25
Start date
2023-01-06
Completion date
Unknown
Last updated
2026-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nursing care for patients undergoing resection of primary hepatic cancer Cancer

Interventions

Random number sequences are generated using SPSS 26.0, stratified by Child-Pugh score (A/B grade), with a block size of 4 for each stratum. Sealed opaque envelopes are used to store allocation results
Postoperative pain management (VAS score = 3): Close monitoring of patients' pain, bowel movements, and drainage tube conditions after surgery
Early ambulation (within 24 hours postoperatively): Guidance on early ambulation to actively prevent complications. A targeted assessment of the condition of enrolled liver cancer patients is conducte

Sponsors

The First Affiliated Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meeting the surgical indications outlined in the "Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition)" (single tumor diameter = 5 cm, no portal vein trunk tumor thrombus, Child-Pugh A/B grade) 2. Age 18-75 years 3. Signed informed consent

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular disease (NYHA III-IV grade) 2. Immune system disease or coagulation dysfunction (INR > 1.5, PLT < 50 × 10^9/L) 3. Malignant tumors in other locations 4. History of cognitive impairment or mental illness.

Design outcomes

Primary

MeasureTime frame
1. Psychological stress response is measured using Psychological Stress Response Questionnaire (SRQ) at one day before surgery, three days after surgery , and at discharge. 2. Depressive state is measured using Hamilton Depression Scale (HAMD) at one day before surgery, three days after surgery , and at discharge. 3. Anxiety level is measured using Hamilton Anxiety Scale (HAMA) at one day before surgery, three days after surgery , and at discharge.

Secondary

MeasureTime frame
Measured using patient records: 1. Recorded the time to tolerate semi-liquid diet (time from surgery to first intake of =200 mL semi-liquid food) 2. Time to first out-of-bed activity (time from surgery to independent standing and walking =5 meters) 3. Time to first postoperative anal exhaust, and length of hospital stay

Countries

China

Contacts

Public ContactQinhong Xu
xuqinhong_xqh03@126.com+86 0574 87085014

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 22, 2026