Surgery: Anaesthesia Surgery Anaesthesia
Conditions
Interventions
On arrival in the anaesthetic room, standard monitoring will be applied
peripheral pulse oximeter (SpoO2), electrocardiogram (ECG), non invasive blood pressure (NIBP), and intravenous access sited.
The anaesthetist will open an envelope randomly allocating the patient in
Sponsors
Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
Eligibility
Inclusion criteria
Inclusion criteria: 30 patients will be required in each group in the study. To our knowledge there are no studies of direct comparison between techniques using either suxamethonium or remifentanil for intubation in the paediatric population. We have found no studies assessing intubating condition, cardiovascular response and apnoea time in children at a lower dose of remifentanil of 1.25 mcg/kg. This would be possible in children presenting for surgery, who would already require general anaesthesia and intubation and in whom paralysis is not a requirement for surgery itself.
Exclusion criteria
Exclusion criteria: Not provided at time of registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Heart rate, blood pressure, oxygen saturation and end tidal carbon dioxide as part of normal anaesthesia. Apnoea time from end of propofol injection to first recognisable breath. Intubation conditions 2. Intubating condition scores: Jaw relaxation score: 1 - Relaxed, 2 - Raised Tone, 3 - Rigid Laryngoscopy score: 1 - Easy, 2 - Difficult, 3 - Impossible Vocal cords score: 1 - Open, 2 - Moving, 3 - Closed Coughing score: 1 - None, 2 - Slight, 3 - Severe Limb movement score: 1 - None, 2 - Slight, 3 - Severe All score 1 = excellent, some score 2 = good, any score 3 = poor. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed