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Bolus thrombolysis in cardiac arrest: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN81334888
Enrollment
Unknown
Registered
2003-09-12
Start date
2002-09-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Bolus thrombolysis Circulatory System Bolus thrombolysis

Interventions

Single bolus dose tenecteplase or placebo given after first iv adrenaline on arrival in Accident and Emergency. Questionnaire to be completed by staff and collected by researcher. Added 30/08/10: tri

Sponsors

Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients attending Accident and Emergency with out-of-hospital cardiac arrest 2. Aged 16-79 years old

Exclusion criteria

Exclusion criteria: 1. Inappropriate for resuscitation 2. Late pregnancy

Design outcomes

Primary

MeasureTime frame
Survival (numbers), adverse events/bleeding, neurological status of survivors.

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026