Poor correlation between spectrophotometric intracutaneous analysis and histopathology in melanoma and non-melanoma lesions

Comparison of diagnostic information from spectrophotometric intracutaneous analysis and histopathology in melanoma and non-melanoma lesions: an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN81210311

Enrollment

Registered

2010-02-18

Start date

2004-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melanoma Cancer Malignant neoplasm of skin

Interventions

The included lesions were SIAscopically imaged and documented before excision and histopathological preparation. A specially developed preparatory and documentary procedure was undertaken to find the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Lesions clinically suspicious for melanoma and showing positive SIAscopic findings during routine investigations

Exclusion criteria

Exclusion criteria: Aged under 18 years

Design outcomes

Primary

Measure	Time frame
1. SIAgraphs were evaluated for features indicating melanoma and the following were calculated: 1.1. Sensitivity 1.2. Specificity 1.3. Positive Predictive Value (PPV) 1.4. Negative Predictive Value (NPV) 2. Topographical comparisons between SIAscopy findings and histopathology were made. Level of agreement was assessed by Kappa statistics.	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026