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Effect of hyperbaric oxygen on recovery from exercise-induced fatigue

Effect of hyperbaric oxygen after moderate-intensity exercise on fatigue: a single-blind crossover randomized trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN81080077
Enrollment
9
Registered
2025-01-14
Start date
2012-08-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participants with fatigue after moderate-intensity exercise Other

Interventions

The study used a crossover design in which all subjects received both the hyperbaric oxygen (HBO) intervention and air placebo following with an interval of 1 week. The subjects were randomly assigned

Sponsors

Tokyo Medical and Dental University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Healthy male university students who exercised regularly

Exclusion criteria

Exclusion criteria: 1. Participant had difficulty relieving pressure in their ears (which precludes or makes HBO treatment difficult) 2. Claustrophobia 3. Congenital pulmonary cysts 4. Asthma 5. History of pneumothorax or heart disease 6. Experienced heart palpitations, precordial pain, or tachycardia during the previous year

Design outcomes

Primary

MeasureTime frame
Whole-body fatigue and leg fatigue were measured using the visual analogue score (VAS) at pre-exercise (test 1), post-exercise (test 2), post-intervention (test 3), 1.5 h post-intervention (test 4), and 24 hours post-intervention (test 5).

Secondary

MeasureTime frame
Muscle fatigue, inflammation, and the immune system assessed using blood tests at pre-exercise (test 1), post-exercise (test 2), post-intervention (test 3), 1.5 h post-intervention (test 4), and 24 hours post-intervention (test 5).

Countries

Japan

Contacts

Public ContactKazuyoshi Yagishita
yagishita.orth@tmd.ac.jp+81-3-5803-5341

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026