Prevalence of psychological consequences of stroke Mental and Behavioural Disorders
Conditions
Interventions
The purpose of the long-term follow-up assessments is to provide in-depth neuropsychological profiling using clinical screening tools in combination with more detailed cognitive testing batteries. Tes
Sponsors
University of Oxford
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: OX-CHRONIC directly leverages existing data. A cognitive screening programme based within the acute stroke unit, capturing the Oxfordshire area has been ongoing since 2012. Participants in this study have been assessed for stroke specific cognitive impairments during acute recovery and at six-month follow-up. Participants agree to be followed up 6 months later with a home visit to assess psychological consequences of stroke and quality of life. Participants who completed the follow-up and gave explicit opt-in consent for re-contacting for further research will be contacted to take part in this two-year follow-up study. Importantly, there is a minimum two-year interval between stroke and the first new assessment for OX-CHRONIC.
Exclusion criteria
Exclusion criteria: 1. The participant is too unwell to be able to stay awake or concentrate for 30 minutes 2. The participant or consultee/proxy has insufficient English comprehension to complete assessments,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Dementia status using DSM-5 criteria and based on medical records, cognitive testing and impairment in function of activities of daily living assessed by two trained physicians at wave 1 and wave 2 2. Domain specific impairment is measured using the Oxford Cognitive Screen (OCS) at wave 1 and wave 2. 3. Global cognitive impairment is measured using the Montreal Cognitive Assessment (MoCA) at wave 1 and 2. 4. Activities of daily living is assessed using Nottingham Extended ADL at wave 1 and 2. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Language abilities measured using the Boston Naming Test at wave 1 and 2. 2. Verbal Fluency measured using the Letter Fluency and Categories fluency tests at wave 1 and 2. 3. Executive function measured using the Hayling Test, Trails Making Tests A and B, and OCS-Plus Trails at wave 1 and 2. 4. Working Memory measured using the Digit Span Forwards and Backwards test at wave 1 and 2. 5. Episodic Memory measured using the Logical Memory Test Part 1 and 2, and the Picture Memory Test at wave 1 and 2. 6. Visual Spatial Ability measured using the OCS-Plus Figure Copy test and the Rey Complex Figure Copy Test at wave 1 and 2. 7. Spatial Attention measured using the Star Cancellation test at wave 1 and 2. 8. Mood disorders measured using the Hospital Anxiety and Depression Scale, Geriatric Depression Scale, and the Apathy Evaluation Scale at wave 1 and 2. 9. Fatigue measured using the Fatigue Severity Scale at wave 1 and 2. 10. Sleep Quality measured using the Sleep Condition Indicator at wave 1 and 2. 11. Cognitive Reserve measured using the Cognitive Reserve Index at wave 1 and 2. 12. Quality of life measured using the Stroke Impact Scale, and the EQ-5D-5L at wave 1 and 2. 13. Care-giver perspectives measured using the Informant Questionnaire on Cognitive Decline in the Elderly, Caregiver Strain Index, and Informant Assessed Geriatric Depression Scale at wave 1 and 2. | — |
Countries
England, United Kingdom
Outcome results
None listed