Sedation and pain management in mechanically ventilated neurointensive care patients Nervous System Diseases
Conditions
Interventions
100 participants were recruited while the previous sedation practice was in effect, and new 100 participants were recruited after the introduction of the new sedation protocol (200 participants recrui
Sponsors
Copenhagen University Hospital (Denmark)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Both males and females, >17 years old 2. Admitted to the neurointensive care unit (NICU) 3. Tracheally intubated within 24 hours 4. Mechanically ventilated 5. Receiving continuous infusions of sedatives and analgesics
Exclusion criteria
Exclusion criteria: 1. Potential organ donors 2. Non-sedated and non-intubated patients 3. Patients transferred intubated from other units
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. A shift from sedation-based to analgesia-based sedation (analgo-sedation), assessed from the chages in the use of sedatives and analgesic agents in each patient 2. Improved pain management, assessed daily in each patient using the Pain Intensity (PI) scale For all primary and secondary outcome measures, the participants were followed-up until they were off mechanical ventilation and sedation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of late pneumonia. Late pneumonia was defined as pneumonia acquired >48 hours after intubation. 2. Accidental extubations 3. Duration of sedation For all primary and secondary outcome measures, the participants were followed-up until they were off mechanical ventilation and sedation. | — |
Countries
Denmark
Outcome results
None listed