Asthma Respiratory Asthma
Conditions
Interventions
Low sodium diet versus normal sodium diet.
Sponsors
University of Nottingham (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 - 65 years, either sex 2. Asthma 3. Bronchial reactivity to methacholine
Exclusion criteria
Exclusion criteria: 1. Oral steroids 2. Diuretics or drug that affects sodium 3. Current or planned pregnancy 4. Other serious illness 5. Recent exacerbation of asthma
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Peak flow rate, measured for one week before baseline visit and for the six weeks of the study 2. Symptom score, measured for one week before baseline visit and for the six weeks of the study 3. Spirometry, measured at baseline visit and six weeks later 4. Skin prick sensitivity, measured at baseline visit and six weeks later 5. Carbon monoxide, measured at baseline visit and six weeks later | — |
Primary
| Measure | Time frame |
|---|---|
| 1. Bronchial reactivity, measured at baseline visit and six weeks later 2. Autonomic function assessed by heart rate variability, measured at baseline visit and six weeks later | — |
Countries
United Kingdom
Outcome results
None listed