Prostate cancer Cancer
Conditions
Interventions
1. Supervised physical exercise program:
The patients in the exercise group (EG) performed moderate-intensity physical exercise 5 days per week. The study exercise program began before
Sponsors
Greater Poland Cancer Centre
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 75 years 2. Scheduled ADT (LH-analogue 10.8 mg every 3 months) planned to continue for a total period of 36 months (3 to 5 months prior to RT, during and after completion) 3. RT received a total dose of 76 Gy in 38 fractions (in the first phase of therapy, the pelvic lymph nodes along with the prostate gland and seminal vesicles were subjected to a dose of 46 Gy at 2 Gy fractions and in the second phase of therapy the irradiated volume was limited to prostate gland plus seminal vesicles to a total dose of 76 Gy), 4. Good general condition (Eastern Cooperative Oncology Group - ECOG- performance status 0-1)
Exclusion criteria
Exclusion criteria: 1. Distant metastases and/or disease progression resulting in RT or the introduction of chemotherapy 2. Insufficiently controlled arterial hypertension or cardiac diseases resulting in circulation failure (above Stage II Heart Failure according to the New York Heart Association) 3. Insufficiently controlled metabolic diseases, endocrinological, rheumatic, and absorption disorders 4. Other tumours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Efficacy of physical exercises (data from questionnaires) 2. Blood inflammation markers 3. Assessment of functional capacity, fatigue and QoL during PCa treatment They are measured before radiotherapy ( baseline), after 8 weeks, and after 10 months (12 month follow-up). | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation (the relationship) between changes in inflammatory parameters with fatigue and QoL scores. | — |
Countries
Poland
Outcome results
None listed