Dentin hypersensitivity in adults with at least one anterior tooth exhibiting cervical or gingival recession and sensitivity to tactile or air stimulation. Oral Health
Conditions
Interventions
This is a single-centre, randomized, double-blind, placebo-controlled, parallel-group clinical trial conducted to evaluate the immediate and sustained effects of desensitizing toothpastes on dentin hy
Sponsors
Lion Corporation (Japan)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 18–65 years in good general health 2. At least one dentin-sensitive tooth with cervical or gingival recession, sensitive to tactile stimulation (10–50 g) or air stimulus (Schiff score = 2) 3. Able to attend all scheduled examinations during the 8-week study period 4. Willing to provide written informed consent
Exclusion criteria
Exclusion criteria: 1. Severe systemic or chronic diseases 2. Advanced periodontal disease or periodontal treatment within the past year 3.Teeth with extensive restorations, suspected chronic pulpitis, caries, or enamel cracks 4. Current use of desensitizing toothpaste or participation in other clinical trials within the past 3 months 5. History of allergy to oral care products or ingredients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dentin hypersensitivity measured using the Dentin Sensitivity Index (DSI) for tactile stimulation (Yeaple probe, grams) and air stimulation (Schiff score) at baseline, immediately after brushing, and at 2, 4, and 8 weeks of toothpaste use | — |
Secondary
| Measure | Time frame |
|---|---|
| The immediate desensitizing effect after a single brushing measured using the Dentin Sensitivity Index (DSI) for tactile and air stimulation at the initial visit;The sustained desensitizing effect measured using the Dentin Sensitivity Index (DSI) for tactile and air stimulation at 24 hours, following 4 weeks of use | — |
Countries
China
Contacts
Public ContactZhi Zhou
Outcome results
None listed