Hyperemesis gravidarum Pregnancy and Childbirth
Conditions
Interventions
Participants are randomized to:
1. Delayed oral intake (fasting) for the first 12 hours after hospitalisation for hyperemesis gravidarum followed by resumption of taking fluids and sol
Sponsors
University of Malaya (Malaysia)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of hyperemesis gravidarum 2. First hospitalisation for hyperemesis gravidarum in current pregnancy 3. Presence of ketonuria by urine dipstick (of 2+ or greater) at hospitalisation 4. At least 18 years of age 5. Pregnancy gestation of 14 weeks or less
Exclusion criteria
Exclusion criteria: 1. Multiple pregnancy 2. Molar pregnancy 3. Confirmed non-viable pregnancy 4. Any medical condition that contraindicates oral feeding or fasting
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Frequency of vomiting in the first 24 hours 2. Nausea score (using a Visual Numerical Rating Scale from 0 to 10) at enrollment, 8, 16 and 24 hours 3. Patient’s satisfaction score (using a Visual Numerical Rating Scale from 0 to 10) at 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of hospitalisation 2. Ketonuria at 24 hours 3. An 8-item symptoms questionnaire at 24 hours 4. Participant preference on feeding regimen in a future hospitalisation for hyperemesis gravidarum at 24 hours 5. Participant recommendation of their feeding regimen to a friend in the same circumstances at 24 hours | — |
Countries
Malaysia
Contacts
Public ContactPeng Chiong Tan
Outcome results
None listed