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The effect of local anaesthetic on skin graft thickness and cell culture

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN80435760
Enrollment
Unknown
Registered
2006-09-29
Start date
2005-10-08
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Skin graft Surgery Skin graft

Interventions

EMLA cream is frequently used in the harvesting of split skin grafts. It provides sufficient anaesthesia for grafts to be taken without any supplemental anaesthetic agent. Reports suggest the applicat

Sponsors

Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing abdominoplasty surgery will be recruited for the trial. These patients will be recruited from clinics where they have attended for discussion of the procedure. The area of skin to be discarded as part of the routine abdominoplasty procedure will be used for the trial. If the patient agrees to participate written consent will be obtained. Inclusion criteria include: 1. Low anaesthetic risk patients (ASA I) 2. Previous sensitivity to opsite, EMLA, lidocaine or prilocaine, as these are the materials to be tested. Long term steroid use, as this affects the structure of the skin (by thinning it), and can affect wound healing, which may adversely affect the cell culture

Exclusion criteria

Exclusion criteria: Long term steroid use, previous adverse reaction to EMLA, prilocaine or lidocaine.

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026