Optical treatment of nystagmus

A quantitative study comparing hard and soft contact lenses to spectacles on changes in nystagmus oscillations

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN80219391

Enrollment

Registered

2010-08-11

Start date

2010-09-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nystagmus Eye Diseases Nystagmus and other irregular eye movements

Interventions

Patients will take part in the trial for a total duration of 8 weeks. This will comprise of 2 weeks of spectacle wear followed by 2 weeks of hard or soft contact lens wear. The next 2 weeks the patien

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Infantile nystagmus over the age of 16 years, either sex

Exclusion criteria

Exclusion criteria: 1. Currently involved in surgical or pharmacological trials for the treatment of nystagmus 2. Previous corneal trauma or intolerence to contact lens wearing

Design outcomes

Primary

Measure	Time frame
Changes in nysatgmus intensity measured with eye movement recordings, measured at baseline, day 14, day 28, day 42 and day 56.	—

Secondary

Measure	Time frame
Measured at baseline, day 14, day 28, day 42 and day 56: 1. Changes in LogMAR (chart) visual acuity at 4M (with head free) 2. Changes in LogMAR (chart) visual acuity at 0.4M (with head free) 3. Change in gaze dependant visual acuity at 4M 4. Change in nystgamus intensity, NAFX function and reading speed will be evaluated from the eye movement recordings at different fixation points across the horizontal plane 5. Subjective changes in visual function evaluated with the VFQ25	—

Measure

Time frame

Measured at baseline, day 14, day 28, day 42 and day 56: 1. Changes in LogMAR (chart) visual acuity at 4M (with head free) 2. Changes in LogMAR (chart) visual acuity at 0.4M (with head free) 3. Change in gaze dependant visual acuity at 4M 4. Change in nystgamus intensity, NAFX function and reading speed will be evaluated from the eye movement recordings at different fixation points across the horizontal plane 5. Subjective changes in visual function evaluated with the VFQ25

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Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026