Respiratory tract infections in healthy adults Infections and Infestations
Conditions
Interventions
This study aims to assess the effectiveness of maintaining physical distance from others in real-life situations. During the intervention, choir participants will be instructed to avoid close contact
Sponsors
Norwegian Institute of Public Health
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for choirs are: 1. The choir comprises at least = 15 members 2. The choir rehearses at least = once a week 3. The majority of the choir members consent to participate in the study and follow the assigned intervention 4. The choir may hold rehearsals in a venue that allow for at least 1.5 meter distance between singers during the study period Inclusion criteria for choir members are: 5. Aged 18 years or older at the day of signing consent 6. Provide informed consent to participate in the study and contribute weekly data Inclusion criteria for choir members for a substudy on adherence to the intervention are (only including a few choirs in the intervention arm): 7. Each choir members are willing to have an assigned place for the duration of each practice, and share information on their location, and 8. All choir members provide consent to be filmed or monitored during rehearsals Inclusion criteria for the reference group participants are: 9. Member of the Norwegian Institute of Public Health survey panel (“FHI-panel”) 10. Resident of the greater Oslo region, Norway 11. Provides informed consent to participate in the study and contribute weekly data
Exclusion criteria
Exclusion criteria: Exclusion criterion for the reference group participants is 1. Regularly attends choir rehearsals
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time to respiratory tract infection (RTI) is measured using a composite of self-reported symptoms via weekly individual questionnaires and positive antigen test results for SARS-CoV-2, influenza A/B, or RSV from study start to last completed questionnaire or end of study period 2. Self-reported RTI symptoms are measured using the Jackson scale in weekly individual questionnaires from study start to last completed questionnaire or end of study period 3. Positive viral infection status is measured using antigen tests for SARS-CoV-2, influenza A/B, and RSV at 2 months 4. Symptom severity is measured using the Jackson scale (0–3 per symptom) in weekly individual questionnaires from study start to last completed questionnaire or end of study period 5. Presence of common cold is measured using self-report in weekly individual questionnaires from study start to last completed questionnaire or end of study period 6. RTI onset is defined as the first occurrence of a self-reported common cold, a Jackson score =2, and at least one of sneezing, nasal discharge, nasal obstruction, or sore throat, measured using weekly individual questionnaires from study start to last completed questionnaire or end of study period 7. Symptom-free and test-negative status at baseline is measured using self-report and antigen testing at study start | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to first positive test for SARS-CoV-2, influenza A/B, or RSV is measured using antigen testing 2. Time to first self-reported respiratory tract infection is measured using weekly individual questionnaires and the Jackson scale 3. Number of days with self-reported symptoms of respiratory tract infection is measured using the Jackson scale in weekly individual questionnaires from study start to last completed questionnaire or end of study period 4. Number of participants with a self-reported respiratory tract infection or positive antigen test is measured using weekly individual questionnaires and antigen testing 5. Distribution of positive tests for SARS-CoV-2, influenza A/B, and RSV is measured using antigen testing | — |
Countries
Norway
Contacts
Public ContactErle Refsum
Outcome results
None listed