Recurrent urinary tract infections Urological and Genital Diseases Urinary tract infections
Conditions
Interventions
Trimethoprim 100 mg daily versus 500 mg cranberry product daily
Sponsors
University of Dundee (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Community dwelling women aged 45 years or over with at least two antibiotic-treated urinary tract infections or episodes of cystitis in the previous 12 months
Exclusion criteria
Exclusion criteria: 1. Previous urological surgery, stone or anatomical abnormalities 2. Urinary catheter 3. Diabetes mellitus 4. Immunocompromised 5. Pyelonephritis 6. Severe renal impairment 7. Blood dyscrasia 8. Symptomatic urinary tract infection (UTI) at baseline 9. Cognitive impairment precluding informed consent 10. Resident in institutional care 11. On longterm antibiotics 12. On warfarin therapy 13. Regular cranberry consumers 14. Unwilling to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measure (as of 21/02/2018:) First recurrence of symptomatic urinary tract infection self reported by patient during 6 month study Previous primary outcome measure: First recurrence of symptomatic urinary tract infection | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures (as of 21/02/2018): Acceptability and adherence, measured by number of capsules left at the end of the 6 month study Previous secondary outcome measure: Acceptability and adherence | — |
Countries
United Kingdom
Outcome results
None listed