Second degree burn wounds Injury, Occupational Diseases, Poisoning Burn of second degree, body region unspecified
Conditions
Interventions
After eligibility was established, an initial evaluation was performed on each patient that included recording subject demographics, medical and social history, and a baseline assessment of the burn i
the physician investigators and other medical personnel were blinded to the type of treatment from the first day of admission until the wounds were completely healed. All patients were treated with fl
Sponsors
National Research Council (Thailand)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 15-60 years of age 2. Second degree burn wounds covering no less than 15% of the total body surface area (TBSA) with no wound infection 3. Patients were to stay at the hospital until the wounds were completely healed
Exclusion criteria
Exclusion criteria: 1. Patients with history of allergy to sulfonamides, sericin, or any of the other ingredients in the formulation 2. Patients who had active diabetes mellitus, chronic obstructive pulmonary disease, psychological problems, dementia, malnutrition or immunodeficiency 3. Patients who experienced abnormal liver or renal function tests prior to enrollment 4. Patients with cancer or receiving chemotherapy and those who were pregnant or breastfeeding 5. Patients who show no response to the treatment, were not willing to continue with the study, or when the physician opined that treatment was no longer needed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The wound size was measured using Visitrak Digital and the healing percentage of the wound was calculated. The length of time to heal was also recorded. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Adverse drug reactions were assessed using Naranjo?s algorithm 2. Pain was assessed in all patients every 7 days using the visual analog scale 30 min after a dressing change 3. Burn health status was also evaluated using Burn-Specific Health Scale-Brief (BSHS-B) | — |
Countries
Thailand
Outcome results
None listed