Implementing and evaluating a structured education programme and a new model of ongoing care for type 1 diabetes: the Irish Dose Adjustment For Normal Eating (DAFNE) study

Conditions

Type 1 diabetes Nutritional, Metabolic, Endocrine Insulin-dependent diabetes mellitus

Adam Raymakers, Paddy Gillespie, Mary Clare O’Hara, Matthew D. Griffin, Seán F. Dinneen

Health and Quality of Life Outcomes2018-02-0224 citations

Cost effectiveness of group follow-up after structured education for type 1 diabetes: a cluster randomised controlled trial

Paddy Gillespie, Eamon O’Shea, Mary Clare O’Hara, Seán F. Dinneen, Sean F Dinneen

Trials2014-06-1415 citations

10.1186/1745-6215-15-227

A longitudinal qualitative study examining the factors impacting on the ability of persons with T1DM to assimilate the Dose Adjustment for Normal Eating (DAFNE) principles into daily living and how these factors change over time.

Casey D, Murphy K, Lawton J, White FF, Dineen S.

2011-08-3015 citations

10.1186/1471-2458-11-672

The Irish DAFNE study protocol: a cluster randomised trial of group versus individual follow-up after structured education for type 1 diabetes.

Dinneen SF, O' Hara MC, Byrne M, Newell J, Daly L, O' Shea D, Smith D, Irish DAFNE Study Group.

2009-09-2320 citations

10.1186/1745-6215-10-88

Interventions

After obtaining informed consent participants will be assigned to the next available DAFNE course in their participating centre. Prior to commencement of the course, baseline data will be collected. I

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with type 1 diabetes for over one year 2. Attending the adult diabetes clinic in one of the participating centres 3. Ability to speak and read English 4. Willingness to monitor blood sugar levels at regular intervals 5. Willingness to transition to a basal/bolus insulin regimen prior to DAFNE training (if not already on such a regimen) 6. Glycosylated haemoglobin (HbA1c) level below 13 percent at recruitment Added as of 13/02/2009: 7. Both males and females, 18 years old or greater Please note that as of 30/07/07, the previous inclusion criteria point six read as: 6. Glycosylated haemoglobin (HbA1c) level between 7.5 and 13 percent at recruitment

Exclusion criteria

Exclusion criteria: 1. Patients with type 2 diabetes 2. Attending a paediatric clinic 3. Pregnant or planning a pregnancy in the next 2 years 4. Presence of advanced diabetic complications (e.g. kidney failure with serum creatinine >250 µmol/L) 5. Serious co-morbidity likely to interfere with study participation 6. Previous DAFNE training or current use of a continuous subcutaneous insulin infusion pump

Design outcomes

Primary

Measure	Time frame
Longitudinal change in mean HbA1c level between baseline and follow-up. Added as of 17/02/2009: All primary and secondary outcomes will be assessed at 6, 12 and 18 months.	—

Secondary

Measure	Time frame
1. Rates of severe hypoglycaemia 2. Change in weight and psychological measures of wellbeing and quality of life Added as of 17/02/2009: The following scales are used to assess psychological measures of wellbeing and quality of life: 1. Hospital Anxiety and Depression Scale (HADS) 2. Problem Areas in Diabetes (PAID) Questionnaire 3. Disease Specific Quality of Life questionnaire (DSQOL) 4. Euroqol EQ-5D 5. Sub-study: comparison of Audit of Diabetes-Dependent Quality of Life (ADDQOL) vs Diabetes Treatment Satisifaction Questionnaire (DTSQ) 6. Health Economics Questionnaire (developed for the study) All primary and secondary outcomes will be assessed at 6, 12 and 18 months.	—

Measure

Time frame

1. Rates of severe hypoglycaemia 2. Change in weight and psychological measures of wellbeing and quality of life Added as of 17/02/2009: The following scales are used to assess psychological measures of wellbeing and quality of life: 1. Hospital Anxiety and Depression Scale (HADS) 2. Problem Areas in Diabetes (PAID) Questionnaire 3. Disease Specific Quality of Life questionnaire (DSQOL) 4. Euroqol EQ-5D 5. Sub-study: comparison of Audit of Diabetes-Dependent Quality of Life (ADDQOL) vs Diabetes Treatment Satisifaction Questionnaire (DTSQ) 6. Health Economics Questionnaire (developed for the study) All primary and secondary outcomes will be assessed at 6, 12 and 18 months.

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Countries

Ireland

Outcome results

None listed