Obesity Nutritional, Metabolic, Endocrine Obesity
Conditions
Interventions
All patients received all three interventions for 16 weeks:
1. The subjects visited an obesity clinic twice per month and restricted their caloric intake to less than their usual intake by 600 kcal/da
Sponsors
Yonsei University College of Medicine (South Korea)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Apparently healthy, either sex, aged 18 - 60 years 2. Non-smokers 3. Low alcohol consumers 4. Overweight or obese with an average Body Mass Index (BMI) of 23 kg/m^2 or greater
Exclusion criteria
Exclusion criteria: 1. A past history of cardiovascular disease 2. Diabetes 3. Moderate to severe hypertension (resting blood pressure greater than 170/100 mmHg) 4. Renal impairment (serum creatinine greater than 120 µmol/L) or overt proteinuria 5. Obesity caused by an endocrine disorder 6. Psychiatric disorders 7. Current pregnancy or breast-feeding 8. A body weight fluctuation of more than 5 kg in the previous six months 9. Taking any kind of medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes of body fat distribution and adipocytokines, determined by computed tomography scan and measured both before and 16 weeks after the weight reduction program. | — |
Secondary
| Measure | Time frame |
|---|---|
| The relationship of body fat distribution and adipocytokines, determined by computed tomography scan and measured both before and 16 weeks after the weight reduction program. | — |
Countries
Korea, South
Outcome results
None listed