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Treating trauma in psychosis

The effect of treatment of posttraumatic stress disorder in people with a lifetime psychotic disorder: a multi-site randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN79584912
Enrollment
240
Registered
2012-02-27
Start date
2011-11-01
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychosis and post-traumatic stress disorder/ psychiatry and psychology Mental and Behavioural Disorders Post-traumatic stress disorder

Interventions

In all three arms treatment as usual will be provided for the psychotic disorder for which the person sought help. In the experimental arms there will be a maximum of 8 sessions (over two months) of e

Sponsors

Stichting tot Steun VCVGZ (Netherlands)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Lifetime psychotic disorder as assessed by MINI 2. PTSD as assessed by CAPS 3. Outpatient 4. Age 18 to 65 years

Exclusion criteria

Exclusion criteria: 1. IQ under 70 2. No competence of the Dutch language 3. Not willing or able to travel to treatment location

Design outcomes

Primary

MeasureTime frame
1. Clinician Administered PTSD Scale (CAPS) diagnosis and severity 2. PTSD Symptom Scale Self-Report (PSS-SR) severity

Secondary

MeasureTime frame
1. Influence on psychosis (PANSS 8-item Remission Tool, GPTS and DRS in case of delusions, AHRS and AVH-BAS in case of auditory hallucinations) 2. Depression (BDI-II) 3. Social functioning (PSP) 4. Adverse events (TTIP Adverse Events Questionnaire) 5. Quality of life and cost-effectiveness (EQ5D, TIC-P)

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 23, 2026