Bladder cancer / invasive disease / Urology Cancer Malignant neoplasm of bladder
Conditions
Interventions
After cystectomy and extended pelvic lymphadenectomy patients are randomized into one of the following groups:
1. Group A: parenteral nutrition is given for 7 days
oral intake with a gastrostomy tube in place is started on day 4 after surgery
2. Group B: oral food is given the first day after surgery. No parenteral nutrition. Saline solution for volume substitut
Sponsors
Inselspital, University Hospital Berne (Switzerland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Consecutive series of 198 patients with invasive bladder cancer scheduled for cystectomy and extended pelvic lymph node dissection 2. Age >18 years
Exclusion criteria
Exclusion criteria: 1. Age <18y 2. Pregnancy 3. No informed consent available 4. Previous radiotherapy to the pelvis 5. Prior bowel surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of postoperative complications according to the Dindo-Clavien classification with particular respect for infections. Measured within the first 30 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Recovery of bowel function (flatulence, passage of stool, nausea, vomiting) 2. Length of postoperative hospital stay 3. Nutritional biochemical variables 3.1. Serum albumin 3.2. Prealbumin 3.3. Total protein Measured by questionnaire and blood samples on postoperative day 1, 3, 7, 10, 14 and 30 days after surgery. | — |
Countries
Switzerland
Outcome results
None listed