Lower respiratory tract infection among children aged under 5 years Infections and Infestations
Conditions
Interventions
This study is designed as a case control study, whereby cases will be matched with controls (matched by age, sex, time of admission ). Cases will be identified at community health center (Puskesmas) a
Sponsors
Universitas Diponegoro [Diponegoro University]
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Cough or difficulty in breathing 2. Fast breathing: 2.1. In children aged 2 to 11 months, with breathing rate =50 breaths per min 2.2. In children aged 12 to 59 months, with breathing rate =40 breaths per min 3. First symptom appearing within the last 14 days 4. Aged under 5 years
Exclusion criteria
Exclusion criteria: 1. Hospitalized for more than 24 h at enrolment 2. Cancer or history of cancer 3. History of long-term (more than 2 months) exposure to steroid drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Etiology (with a primary focus on bacteria and viruses) of LRTI identified using conventional (bacterial culture) and molecular methods. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Risk factors assessed using parents' and guardians' responses to a questionnaire 2. Antimicrobial sensitivity patterns of isolated bacterial pathogens 3. Virus identification using multiplex PCR 4. Pneumococcal serotypes causing pneumonia identified using multiplex PCR and the Quellung reaction | — |
Countries
Indonesia
Contacts
Public ContactVincentia Rizke Ciptaningtyas
Outcome results
None listed