Prevention and treatment of postoperative gastrointestinal dysfunction in patients with colorectal cancer Cancer
Conditions
Interventions
This study is a randomized, single-blind, controlled trial involving patients undergoing elective radical colorectal cancer surgery. Participants will be randomly assigned to either the buccal acupunc
Sponsors
Changzhou Science and Technology Bureau
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old, no gender restrictions 2. Body mass index (BMI) =40 kg/m2 3. American College of Anesthesiologists (ASA) grade I to III 4. Radical resection of colorectal cancer should be performed at the selected time
Exclusion criteria
Exclusion criteria: 1. Long-term use of opioids, psychotropic drugs, non-steroidal drugs, etc 2. A history of alcoholism and/or mental illness 3. Tumor recurrence 4. There is an infection in the cheek, or the coagulation function is abnormal 5. Have trigeminal neuralgia or facial paralysis 6. An enterostomy is required
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first defecation measured using patient self-report from the end of surgery to the first occurrence of bowel movement | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to first flatus measured using patient self-report from the end of surgery to the first passage of gas 2. Time to first tolerate a liquid diet measured using patient self-report from the end of surgery to the first successful intake of a liquid diet without gastrointestinal intolerance 3. Time to first tolerate a semi-liquid diet, measured using patient self-report from the end of surgery to the first successful intake of a semi-liquid diet without gastrointestinal intolerance 4. Postoperative ileus measured using the I-FEED score on postoperative day 4 5. Postoperative pain score measured using the Visual Analog Scale (VAS) at 30 minutes after awakening, 24 hours postoperatively, and 48 hours postoperatively 6. Motilin and gastrin levels measured using the enzyme-linked immunosorbent assay (ELISA) at 30 minutes before surgery, 30 minutes after awakening, and 24 hours postoperatively 7. Quality of life measured using the EORTC QLG Core Questionnaire (EORTC QLQ-C30) at baseline and 30 days postoperatively | — |
Countries
China
Contacts
Public ContactJiang Shen
Outcome results
None listed