A research study in Uganda to test a Family Involvement intervention, designed to improved care for people living in the community with severe mental illness

Testing the effectiveness, acceptability and feasibility of Family Involvement in severe mental illness in Uganda: a non-randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN78948497

Enrollment

120

Registered

2019-03-04

Start date

2018-12-01

Completion date

Unknown

Last updated

2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with severe mental illness (including psychosis) Mental and Behavioural Disorders

Interventions

30 patients will be recruited to the Family Involvement intervention and 30 patients will be recruited to a control condition, against which patient outcomes will be compared. Patient

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with a primary diagnosis of severe mental illness (ICD-10 F20-29, F31, F32) 2. Aged 18-65 years 3. Capacity to provide informed consent assessed by UBACC Score of =14; 4. Able to communicate in Luganda or English 5. Can identify a family member or friend 6. Scores 5 or below on the MANSA scale

Exclusion criteria

Exclusion criteria: 1. Primary diagnosis of substance-use disorder; organic psychosis and/or neurocognitive disorder 2. Currently an inpatient at the time of recruitment 3. Participating in another study conducted by this or another research group

Design outcomes

Primary

Measure	Time frame
Quality of Life measured using the Manchester Short Assessment of Quality of Life (MANSA) at baseline, 6 and 12 months	—

Secondary

Measure	Time frame
1. Objective social functioning, measured using Objective Social Outcome Index (SIX) at baseline, 6 and 12 months 2. Symptoms, measured using Brief Psychiatric Rating Scale (BPRS) at baseline, 6 and 12 months 3. Service use, measured using adapted Client Service Receipt Inventory (CSRI) at baseline, 6 and 12 months 4. Stigma, measured using the Internalized Stigma of Mental Illness Inventory (ISMI) at baseline, 6 and 12 months 5. Medication adherence, measures using the Medication Adherence Rating Scale (MARS) at baseline, 6 months and 12 months	—

Measure

Time frame

1. Objective social functioning, measured using Objective Social Outcome Index (SIX) at baseline, 6 and 12 months 2. Symptoms, measured using Brief Psychiatric Rating Scale (BPRS) at baseline, 6 and 12 months 3. Service use, measured using adapted Client Service Receipt Inventory (CSRI) at baseline, 6 and 12 months 4. Stigma, measured using the Internalized Stigma of Mental Illness Inventory (ISMI) at baseline, 6 and 12 months 5. Medication adherence, measures using the Medication Adherence Rating Scale (MARS) at baseline, 6 months and 12 months

—

Countries

Uganda

Contacts

Public ContactFrancois van Loggerenberg

f.vanloggerenberg@qmul.ac.uk+44 (0)207 540 4380 Ext: 2339

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 2, 2026