Induction of labour Pregnancy and Childbirth Induction of labour
Conditions
Interventions
In patients randomised to receive dinoprostone gel, in nulliparous with an unfavourable cervix (modified bishop score less than 4), an initial dose of 2 mg was administered. In multiparaous and nullip
Sponsors
Queen Charlotte's and Chelsea Hospital (QCCH) (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women undergoing induction of labour with a cephalic presentation (singleton) or first twin cephalic at term (greater than or equal to 36+6 to 42 weeks gestation)
Exclusion criteria
Exclusion criteria: 1. Favourable cervix (defined as a modified Bishop score of greater than or equal to 8) 2. Any contraindication to vaginal birth 3. Previous uterine surgery (including caesarean section) 4. Unwillingness to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time interval between induction of labour to delivery in minutes, irrespective of the mode of delivery, and the rate of failed induction of labour leading to caesarean section. Assessed in every patient during the process of labour induction at gestation (greater than or equal to 36+6 to 42 weeks gestation). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Requirement for oxytocin augmentation 2. Incidence of uterine hyperstimulation, defined as uterine tachysystole (with five or more contractions in a 10 minute period for two consecutive 10 minute periods) or uterine hypertonus (a uterine contraction lasting for more than two minutes) resulting in pathological cardiotocography trace that necessitated intervention by administering of a tocolytic or delivery 3. Incidence of intrapartum foetal blood sampling 4. Epidural requirement 5. Mode of delivery 6. Blood loss at delivery 7. Incidence of maternal pyrexia 8. Perineal lacerations require suturing 9. 1 and 5-minute Apgar score 10. Need for admission to NICU | — |
Countries
United Kingdom
Outcome results
None listed