Is it feasible to take physiological measurements for people with myalgic encephalomyelitis (ME) in their own homes?

Feasibility of investigating oxygen consumption (VO2), heart rate, blood pressure, lactic acid levels, and activity levels of people with myalgic encephalomyelitis during normal daily activities

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN78379409

Enrollment

Registered

2022-08-18

Start date

2021-05-04

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myalgic encephalomyelitis Nervous System Diseases

Interventions

Following obtaining informed consent, due to the energy limitations of the participants, the information sheet and Fatigue Severity scale (FSS) will be sent ahead of time so the participants can read

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People with myalgic encephalomyelitis and healthy controls

Exclusion criteria

Exclusion criteria: 1. Below the age of 18 years 2. People with very severe ME

Design outcomes

Primary

Measure	Time frame
VO2 and respiratory exchange ratio measured using a portable metabolic system at a single timepoint	—

Secondary

Measure	Time frame
1. Heart rate variability using a firstbeat device measured on the day of testing and for up to 5/6 days afterwards 2. Lactic acid using a COSMED device - lactate pro 2 measured on the day of testing and for up to 5/6 days afterwards 3. BP, HR, O2 saturations, Blood Pressure measured using a digital sphygmomanometer, Heart Rate and Oxygen saturations measured using a pulse oximeter, on the day of testing and for up to 5/6 days afterwards 4. Accelerometry using an actigraph device which measures activity levels for up to 5/6 days afterwards	—

Measure

Time frame

1. Heart rate variability using a firstbeat device measured on the day of testing and for up to 5/6 days afterwards 2. Lactic acid using a COSMED device - lactate pro 2 measured on the day of testing and for up to 5/6 days afterwards 3. BP, HR, O2 saturations, Blood Pressure measured using a digital sphygmomanometer, Heart Rate and Oxygen saturations measured using a pulse oximeter, on the day of testing and for up to 5/6 days afterwards 4. Accelerometry using an actigraph device which measures activity levels for up to 5/6 days afterwards

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 8, 2026