Musculoskeletal Diseases: Rheumatoid arthritis (RA) Musculoskeletal Diseases Rheumatoid arthritis (RA)
Conditions
Interventions
Randomised to either the care pathway or conventional outpatient review before any changes to their DMARD therapy are made. The control group (50 subjects) will be the patients receiving standard rheu
Sponsors
Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients attending the Rheumatology service at St Helens & Knowsley NHS Hospitals with active RA, who are on no more than one disease-modifying anti-rheumatic drug (DMARD), will be invited to participate in the study. Inclusion criteria: 1. Patients with active inflammatory polyarthropathy 2. Age 18 or over 3. On no DMARDs or monotherapy 4. Informed consent
Exclusion criteria
Exclusion criteria: 1. Inflammatory disease due to psoriatic arthritis or other clear or suspected cause other than RA 2. Pregnancy at the time of enrolment or planned during the course of the next 3 years 3. On more than one DMARD at time of enrolment 4. Severe systemic disease or major co-morbidity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Larsen radiological score at 1 year and 2 years 2. Health Assessment Questionnaire (HAQ) assessment at baseline and every 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Assessment of remission at 1 and 2 years 2. Number of DMARDs (disease-modifying anti-rheumatic drugs) and dosage at 1 and 2 years 3. Admissions to the ward with active RA during course of the study | — |
Countries
United Kingdom
Outcome results
None listed