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The role of angiography in glaucoma

Regional relationships between peripapillary vascular density assessed by optical coherence tomographic angiography and visual field sensitivity in glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN77990418
Enrollment
100
Registered
2019-03-28
Start date
2018-08-01
Completion date
Unknown
Last updated
2022-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Eye Diseases Glaucoma

Interventions

All participants underwent the following ophthalmic examinations: 1. BCVA measurements, slit-lamp examination, gonioscopy, and IOP measurement with the Goldmann applanation tonometer.

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients: 1. Primary open angle glaucoma 2. Undergoing treatment with drugs Control group: 1. Visited the clinic for regular eye examinations for refractive errors

Exclusion criteria

Exclusion criteria: 1. Best-corrected visual acuity less than 20/40 2. Refractive error outside the range of – 6.0 to + 3.0 diopters 3. Astigmatism beyond ± 3.0 diopters 4. Previous ocular trauma 5. Ocular surgery or laser treatment 6. History of ocular or systemic disease that could affect the optic nerve or visual field

Design outcomes

Primary

MeasureTime frame
Measured at a single examination: 1. Microvascular images and peripapillary vascular density measured using optical coherence tomographic angiography 2. Visual field sensitivity obtained by automated visual field examination using the Humphrey 740 Visual Field Analyzer

Secondary

MeasureTime frame
The diagnostic abilities of the peripapillary vascular density and RNFL thickness for differentiating the control group and glaucoma group (total, mild, moderate-severe subgroups), measured at a single examination

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026