The potential influence of chicken egg consumption on humans

Presence of extracellular vesicles and their miRNA cargo in chicken eggs and their potential to alter gene expression in non-avian species

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN77867213

Enrollment

Registered

2022-04-15

Start date

2014-10-06

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Change in expression of miRNA/mRNA in humans after consumption of egg EVs Nutritional, Metabolic, Endocrine

Interventions

In the first feeding study, five men and two women (ages 24-36 years) are randomly shuffled and assigned into groups: a group fed with two eggs, a group fed with three eggs and a group fed with four e

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults: 1. Ten men (aged 24-36 years) 2. Two women (aged 24-36 years)

Exclusion criteria

Exclusion criteria: 1. Pregnant 2. Smoking 3. Allergic to eggs

Design outcomes

Primary

Measure	Time frame
miRNA expression in blood plasma evaluated using quantitative real-time polymerase chain reaction (RT-qPCR) before and after consumption of hard-boiled eggs using 3, 4.5, 9, 12, 24 hours as timepoints	—

Secondary

Measure	Time frame
miRNA expression in peripheral blood mononuclear cells (PBMCs) evaluated using RT-qPCR before and after consumption of hard-boiled eggs using 3, 4.5, 9, 12, 24 hours as timepoints	—

Countries

United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 9, 2026