Effects of vitamin E and low-dose aspirin, alone or in combination, on Norplant-induced prolonged bleeding

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN77665712

Enrollment

486

Registered

2004-04-01

Start date

2002-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contraception Pregnancy and Childbirth Contraception

Interventions

Patients are randomised to one of four different 10-day oral treatments: 1. 200 mg vitamin E daily 2. 80 mg aspirin daily 3. Both of the above 4. Placebo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women aged 18 - 38 years 2. 1 - 6 months post Norplant insertion 3. Non-lactating 4. Experiencing an episode of vaginal bleeding lasting more than 7 days

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Chile, China, Dominican Republic, Indonesia, Tunisia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026