Coronary artery disease Circulatory System Coronary artery disease
Conditions
Interventions
Participants will be randomised to receive either revascularization or medical therapy. In all cases, patients will be treated by optimal medical therapy that will include maximum-tolerated beta-block
Sponsors
Fundação Zerbini
Fundação de Amparo à Pesquisa do Estado de São Paulo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Coronary artery disease (CAD) associated with documented ischemic cardiomyopathy subject to surgical revascularization
Exclusion criteria
Exclusion criteria: 1. Unsuitable coronary anatomy for revascularization 2. Prior surgical revascularization 3. Implantable heart devices 4. Terminal chronic kidney disease 5. Refusal to sign consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combined primary endpoints will be considered as those that occurred during the study: death from any cause, nonfatal myocardial infarction, stroke and unstable angina requiring additional intervention. All patients will be followed at outpatient visits every 6 months for 5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints, during the study follow-up, will be the graduation of anginal symptoms and also of heart failure. Cardiac decompensation hospitalization will be considered a secondary event. All patients will be followed at outpatient visits every 6 months for 5 year. | — |
Countries
Brazil
Outcome results
None listed