Cohort study for predicting severe disease courses in patients presenting for coronavirus testing to the University of Zurich COVID-19 Testing Center

Predicting hospitalization and poor clinical outcomes in patients presenting for SARS-CoV-2 testing in an outpatient testing center in Switzerland - a prospective cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN77353041

Enrollment

2000

Registered

2020-04-07

Start date

2020-04-08

Completion date

Unknown

Last updated

2020-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 (SARS-CoV-2 infection) Infections and Infestations COVID-19 (SARS-CoV-2 infection)

Interventions

Patients presenting to the UZH COVID-19 Testing Center for SARS-CoV-2 testing will be enrolled in the cohort study. All patients will undergo routine testing at the testing center. The cohort study-sp

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Present to the UZH COVID-19 Testing Center for SARS-CoV-2 testing following a phone-based triage assessing their eligibility for SARS-CoV-2 testing 2. Provide consent for study participation

Exclusion criteria

Exclusion criteria: 1. Unable to follow study procedures 2. Insufficient knowledge of the German, English, French, or Italian language 3. Aged <16 years

Design outcomes

Primary

Measure	Time frame
Hospital admission for any reason among patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. Information will be collected from participants via follow-up phone calls at days 7, 14, and 60 after consultation, as well as via patient records from general practitioners and/or treating physicians in hospitals after 60 days.	—

Secondary

Measure	Time frame
For each of the outcome measures, the information will be collected from patients via follow-up phone calls and patient records from their general practitioners and treating physicians in hospitals. Follow-up will take place at 7, 14 and 60 days after initial consultation for patients tested positive for SARS-CoV-2, and at 14 days after initial consultation for patients tested negative for SARS-CoV-2 1. ICU admission among patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 2. Use of non-invasive mechanical ventilation for patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 3. Use of invasive mechanical ventilation for patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 4. Time to hospital admission from initial consultation for SARS-CoV-2 testing for patients who tested positive for SARS-CoV-2. 5. Time to ICU admission from initial consultation for SARS-CoV-2 testing for patients who tested positive for SARS-CoV-2. 6. Change in health status at 2 days, 7 days, 14 days and 60 days from baseline visit or last outcome assessment in patients who tested positive for SARS-CoV-2 at initial testing. 7. Patient-reported health status of patients who tested positive for SARS-CoV-2 at initial testing at 2 days, 7 days, 14 days and 60 days. 8. COVID-19 related in-hospital mortality, 30-day mortality and 60-day mortality of patients who tested positive for SARS-CoV-2 at initial testing. 9. All-cause in-hospital mortality, 30-day mortality and 60-day mortality of patients who tested positive for SARS-CoV-2 at initial testing. 10. Positive re-testing among patients tested negative for SARS-CoV-2 at initial testing. 11. Furth	—

Measure

Time frame

For each of the outcome measures, the information will be collected from patients via follow-up phone calls and patient records from their general practitioners and treating physicians in hospitals. Follow-up will take place at 7, 14 and 60 days after initial consultation for patients tested positive for SARS-CoV-2, and at 14 days after initial consultation for patients tested negative for SARS-CoV-2 1. ICU admission among patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 2. Use of non-invasive mechanical ventilation for patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 3. Use of invasive mechanical ventilation for patients who tested positive for SARS-CoV-2 within 30 days following initial consultation for SARS-CoV-2 testing. 4. Time to hospital admission from initial consultation for SARS-CoV-2 testing for patients who tested positive for SARS-CoV-2. 5. Time to ICU admission from initial consultation for SARS-CoV-2 testing for patients who tested positive for SARS-CoV-2. 6. Change in health status at 2 days, 7 days, 14 days and 60 days from baseline visit or last outcome assessment in patients who tested positive for SARS-CoV-2 at initial testing. 7. Patient-reported health status of patients who tested positive for SARS-CoV-2 at initial testing at 2 days, 7 days, 14 days and 60 days. 8. COVID-19 related in-hospital mortality, 30-day mortality and 60-day mortality of patients who tested positive for SARS-CoV-2 at initial testing. 9. All-cause in-hospital mortality, 30-day mortality and 60-day mortality of patients who tested positive for SARS-CoV-2 at initial testing. 10. Positive re-testing among patients tested negative for SARS-CoV-2 at initial testing. 11. Furth

—

Countries

Switzerland

Contacts

Public ContactJan Fehr

jan.fehr@uzh.ch+41 44 634 46 79

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026