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Development of a chart that can be used to aid prediction of hidden cancerous growths in colorectal cancer patients before surgery

Predicting preoperative occult peritoneal metastasis in colorectal cancer patients: Development and external validation of a nomogram and study of its utility

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN76852032
Enrollment
500
Registered
2022-03-16
Start date
2007-08-30
Completion date
Unknown
Last updated
2023-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Predicting preoperative occult peritoneal metastasis in colorectal cancer patients Cancer

Interventions

All enrolled patients were initially diagnosed as PM-negative by CT readings, but later confirmed with the actual PM status during the laparoscopic exploration. The patients were divided into two coho

Sponsors

The Sixth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Current inclusion criteria as of 28/03/2022: 1. Patients were diagnosed with CRC by endoscopy-biopsy pathology, combined with CT and/or other examinations 2. Patients had only one malignant primary tumor 3. Patients did not undergo previous resection of the primary tumor 4. Patients underwent both enhanced CT and laparoscopic exploration Previous inclusion criteria: 1. Diagnosed CRC by endoscopy-biopsy pathology, combined with CT and/or other examination 2. With no other malignant primary tumours 3. With no previous abdominal malignancies or inflammatory diseases 4. With no previous resection of primary tumour 5. With both enhanced CT and laparoscopic exploration.

Exclusion criteria

Exclusion criteria: Current exclusion criteria as of 28/03/2022: 1. Typical PM signs on CT 2. Other distant metastases 3. Previous inflammatory diseases Previous exclusion criteria: 1. With typical PM signs on CT 2. With other distant metastases 3. Incomplete or missing information

Design outcomes

Primary

MeasureTime frame
The actual PM status confirmed using the intraoperative or postoperative histological evaluations at a single time point

Secondary

MeasureTime frame
The predictive accuracy measured using receiver operating characteristic curve and calibration curves at a single time point

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 11, 2026