Grade-2 hamstring tear Musculoskeletal Diseases
Conditions
Interventions
Treatment
1. SIngle 3ml injection of platelet-rich-plasma (PRP) into the injured area under ultrasound guided injection
2. Single 3ml injection of normal saline (Contro
Sponsors
National Sports Institute of Malaysia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Grade-2 hamstring injury diagnosed on clinical assessment and confirmed on ultrasonography 2. Aged = 18 years 3. Acute hamstring muscle injury (= seven days) 4. Able to understand and follow the study protocol and had completed the written informed consent form
Exclusion criteria
Exclusion criteria: 1. Previously received any form of injection therapy for the current injury 2. Using anti-inflammatory drugs (NSAIDs) within one week before randomization 3. Unable to fulfill weekly follow-up appointments and comply rehabilitation program 4. Significant cardiovascular, renal, hepatic disease, malignancy, history of anemia, and previous muscle surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of return-to-play (DRP). DRP is defined as the duration (in days) from the date of injury onset until the participants fulfilled the return-to-play (RTP) criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pain measured using the Brief Pain Inventory–Short form (BPI-SF) at baseline and then once a week (at follow-up assessment) until participants have fully recovered. 2. Recurrence of injury within the next 6 months following recovery. Participants will be monitored via telephone on a monthly basis for 6 months following RTP, in the event of suspicion of re-injury, participants were advised to consult the clinic and the study coordinator as soon as possible. Acute hamstring injury over the same site occurring within the first 6 months following RTP was classified as re-injuries. | — |
Countries
Malaysia
Outcome results
None listed