Early pregnancy Pregnancy and Childbirth
Conditions
Interventions
Patients will be randomised in to one of 2 groups.
Group 1 will be randomised to having probability of viability score and group 2 no score. Group 1 will have bloods taken for progesterone.
Contact
Sponsors
King's College Hospital NHS Foundation Trust (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women (16-40 years) with a positive urine pregnancy test (Clearview HCG II ) 2. Who have conceived spontaneously and have a single intrauterine gestational sac of <20mm mean gestational sac diameter (GSD) with no visible embryo on their first ultrasound scan. A yolk sac is not considered to be a visible embryo so these women will be included.
Exclusion criteria
Exclusion criteria: 1. Assisted conception 2. Multiple pregnancy 3. Use of exogenous progesterone 4. Women who decline to participate 5. Women who intend to terminate the pregnancy 6. Women receiving treatment or investigation for psychiatric disorder 7. Non-English speaking [Hospital Anxiety and Depression Scale (HADS) not validated in other languages]
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in HADS at 7 days between cases and controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Prior to the re-scan 14 days from the initial scan group 1 will be asked two questions in order to establish if the patient found the test helpful. 1. Was it useful to receive the test result? 2. Would they choose to have the test again if they were in a similar position? | — |
Countries
United Kingdom
Outcome results
None listed