Traveller's diarrhoea, prebiotics, lactobacillus, bifidobacterium Infections and Infestations traveller's diarrhoea
Conditions
Interventions
Ecologic Travel ®, a multispecies probiotic product versus a placebo. Intervention consists of one sachet probiotics in powder form containing the following strains: Bifidobacterium bifidum, Lactobaci
Sponsors
Academic Medical Centre (AMC) (The Netherlands)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Both male and female adults (+18) 2. Travelling to high risk area's for Traveller's Diarrhoea (TD) (Middle East, Asia, South and Central America, North Africa) 3. Duration of travelling: min. seven days, max. 28 days 4. People who experienced TD before 5. All new travellers to high risk areas
Exclusion criteria
Exclusion criteria: 1. Use of antibiotics until two weeks before leaving 2. Use of laxatives, acid blockers and diarrhoea inhibitors 3. Persons who already have complaints about their stomach and/or intestines 4. Irritable Bowel Syndrome (IBS)/Irritable Bowel Disease (IBD) and stoma patients 5. Pregnant or breastfeeding women 6. Patients with a serious disturbed or fragile/weak immune system (according to the Dutch National Coordination Center for Travelers' Health Advice [LCR] criteria) 7. Use of probiotics two weeks before start of journey 8. Frequent traveller's to high risk area's who never had TD complaints
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Consistency of stools according to Bristol scale 2. Frequency of stools | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of traveller's diarrhoea | — |
Countries
Netherlands
Outcome results
None listed