Comparison of two mouth rinses (Triphala and Listerine) in patients undergoing fixed orthodontic therapy

Comparing efficacy of 0.6% Triphala with Listerine mouth rinse on gingival health during fixed orthodontic therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76770396

Enrollment

Registered

2018-04-19

Start date

2016-06-20

Completion date

Unknown

Last updated

2018-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival inflammation and associated enlargement, plaque commonly seen in patients undergoing fixed orthodontic treatment Oral Health

Interventions

Patients were assigned to one of two groups by block randomization, single blind masking: 1. Reference arm: Listerine mouth rinse 2. Active arm: 0.6% Triphala mouth rinse Both groups are assessed on

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 18-30 years 2. Minimum of 20 teeth 3. Patients undergoing fixed orthodontic therapy with initial teeth alignment completed 4. Good general health - absence of any systemic illness 5. Gingival enlargement grade 1 or 2 (bokenkamp) 6. Gingival index above 2 (Modified Gingival Index by Lobene)

Exclusion criteria

Exclusion criteria: 1. Known hypersensitivity to the mouth rinses under study 2. Active periodontitis 3. Hard and soft tissue tumours 4. Oral red and white lesions 5. Antibiotic therapy in past 30 days 6. Use of mouthwash in the last 3 months 7. Medications with an effect on oral tissues 8. Habits: smoking, tobacco/paan chewing

Design outcomes

Primary

Measure	Time frame
Gum inflammation and associated gingival enlargement, assessed using Modified Gingival Index and Seymour Gingival Enlargement Index at baseline, 7, 14 and 30 days	—

Secondary

Measure	Time frame
Plaque build up and oral hygiene status, assessed using Plaque Index and Simplified Oral Hygiene Index at baseline, 7, 14 and 30 days	—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026