Metastatic infection/ gram-positive bacteraemia Infections and Infestations Metastatic infection/ gram-positive bacteraemia
Conditions
Interventions
FDG-PET will be performed within 14 days after initiation of treatment. The attending physician will be informed of the results of FDG-PET immediately. Special attention will be paid to confirmation o
Sponsors
University Medical Centre St. Radboud (The Netherlands)
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients with blood cultures containing one of the following micro-organisms: a. Streptococcus aureus b. Streptococcus species (excluding S. pneumoniae) c. Enterococcus species 2. AND at least one of the following risk factors for metastatic infection: a. Community acquired infection b. Signs of infection for more than 48 hours before initiation of appropriate treatment c. Skin lesions or other symptoms or signs pointing to possible metastatic infection d. Fever lasting for more than 72 hours after initiation of appropriate treatment e. Positive blood cultures for more than 48 hours after initiation of appropriate treatment 3. Informed consent
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years 2. Polymicrobial infection 3. Pregnancy 4. Critically ill patients initially admitted to the Intensive Care Unit (ICU) department for more than 14 days 5. Chemotherapeutically induced neutropenia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse rate of infection | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Attributable mortality 2. Mortality after relapse 3. Duration of first admission 4. Duration of antibiotic treatment 5. Number of diagnostic procedures performed to confirm metastatic foci, duration of admission due to relapse 6. Associated costs | — |
Countries
Netherlands
Outcome results
None listed