Sleep disordered breathing and the impact of nocturnal non-invasive ventilatory support on quality of life in motor neurone disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76330611

Enrollment

102

Registered

2004-01-23

Start date

2000-01-10

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous system diseases: motor neurone disease Nervous System Diseases Motor neurone disease

Interventions

1. Early intervention with non-invasive ventilation 2. Standard care

Eligibility

Inclusion criteria

Inclusion criteria: Patients with motor neurone disease under 75 years of age and without other serious illnesses.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Quality of life 1. Generic instrument: Short Form 36 2. Specific instruments: Chronic Respiratory Disease Index, Sleep Apnoea Quality of Life Index, Epworth Sleepiness Scale	—

Secondary

Measure	Time frame
1. Survival 2. Impact on primary carer: Care Givers Strain Index 3. Hospital admissions 4. Respiratory function: Vital capacity, maximum static mouth pressures, sniff nasal inspiratory pressure	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026