A study examining the importance of genetic variation for the ability of severely ill anorectic women to gain weight during three years

The significance of the FTO gene on weight gain and body composition in young Swedish women with severe anorexia nervosa: a three-year follow-up study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76310580

Enrollment

Registered

2020-01-15

Start date

2012-02-01

Completion date

Unknown

Last updated

2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa Mental and Behavioural Disorders Anorexia nervosa

Interventions

Participants were treated for 12 weeks with a high-energy diet. FTO was genotyped and body composition parameters were assessed by dual-energy X-ray absorptiometry and peripheral quantitative computed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Age between 16 and 24 years 2. Diagnosis of anorexia nervosa according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition

Exclusion criteria

Exclusion criteria: 1. Age under 16 years 2. Age above 25 years 3. Individuals with diabetes mellitus or inflammatory bowel disease

Design outcomes

Primary

Measure	Time frame
BMI and body composition parameters measured with dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) at baseline, after 12 weeks of intensive nutrition therapy and after 3 years	—

Secondary

Measure	Time frame
The frequency and duration of physical activity per week evaluated with the International Physical Activity Questionnaire (IPAQ) at 3 years after nutrition therapy	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026