Probiotic cheese in hypocaloric diet

Study of the efficiency of dietary inclusion of a probiotic product containing Lactobacillus plantarum Tensia™ DSM 21380 in obese patients with arterial hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76271778

Enrollment

Registered

2012-11-15

Start date

2010-11-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome with hypertension Nutritional, Metabolic, Endocrine

Interventions

Standard treatment with hypocaloric diet with 50g of regular cheese for control group. Standard treatment with hypocaloric diet with 50g/day probiotic cheese for test group.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 30-69 years 2. Diagnosis of metabolic syndrome characterized by obesity accompanied with arterial hypertonia (>130/85 mm Hg) 3. Absence of decompensated chronic diseases needing intensive treatment 4. Informed consent

Exclusion criteria

Exclusion criteria: 1. A history of gastrointestinal disease 2. Food allergy and acute infection 3. Use of any antimicrobial agent within the preceeding month 4. Pregnancy and breastfeeding 5. No wish to participate

Design outcomes

Primary

Measure	Time frame
1. Significant decrease of blood pressure 2. Significant decrease of body mass index (BMI)	—

Secondary

Measure	Time frame
Colonization of GI tract with L. plantarum Tensia	—

Countries

Russian Federation

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026