The evaluation of a training for patients with hepatitis C to improve their quality of life

Problem solving therapy for patients with hepatitis C to improve quality of life

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76212203

Enrollment

300

Registered

2015-11-03

Start date

2007-05-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis C Infections and Infestations Chronic hepatitis C

Interventions

The participants are randomly allocated to one of two groups. Group 1: Participants take part in seven 1.5-hour sessions of problem solving therapy (PST). PST involves a training in systematic proble

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over 2. Chronic hepatitis C

Exclusion criteria

Exclusion criteria: 1. Unable to fill out a questionnaire (e.g. because of language problems or cognitive impairment) 2. Patients with a psychiatric disorder 3. Patients who are being treated with Interferon

Design outcomes

Primary

Measure	Time frame
Quality of life measured using the Short Form Health Survey (SF-36) at baseline, after the last session (7 weeks), and 6 months after the intervention.	—

Secondary

Measure	Time frame
1. Liver disease symptoms measured using the Liver Disease Symptom Index (LDSI) at baseline, after the last session (7 weeks), and 6 months after the intervention 2. Depression measured using the Beck Depression Inventory (BDI) at baseline, after the last session (7 weeks), and 6 months after the intervention 3. Health care utilisation and production loss measured using the Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness (TiC-P) at baseline, after the last session (7 weeks), and 6 months after the intervention	—

Measure

Time frame

1. Liver disease symptoms measured using the Liver Disease Symptom Index (LDSI) at baseline, after the last session (7 weeks), and 6 months after the intervention 2. Depression measured using the Beck Depression Inventory (BDI) at baseline, after the last session (7 weeks), and 6 months after the intervention 3. Health care utilisation and production loss measured using the Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness (TiC-P) at baseline, after the last session (7 weeks), and 6 months after the intervention

—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026