Randomised controlled trial of nocturnal insulin glargine versus human insulatard in combination with metformin in patients with type two diabetes currently treated with metformin/insulatard combination therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN76123473

Enrollment

Registered

2003-09-12

Start date

2001-08-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

Randomised controlled trial. Patients randomised to: 1. Nocturnal insulin glargine 2. Human insulatard in combination with metformin

Eligibility

Inclusion criteria

Inclusion criteria: 80 patients.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
1. Glycosylated haemoglobin (HbA1c) 2. Tasting blood glucose 3. Frequency of hypoglycaemia 4. Weight change	—

Secondary

Measure	Time frame
Well being and diabetes treatment satisfaction measured using appropriate validated questionnaires.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026