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Comparing soft drink vs Carbex for double contrast upper GI studies

Comparing soft drink vs Carbex for double contrast upper GI studies: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN75939860
Enrollment
200
Registered
2014-07-08
Start date
2014-07-18
Completion date
Unknown
Last updated
2018-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral and Gastrointestinal Digestive System

Interventions

Participants are randomly allocated to one of two groups 1. Test group - drink soft drink (Indian tonic water or ginger ale) before taking barium 2. Control group - drink Carbex before taking barium A

Sponsors

South Devon Healthcare NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Any patient referred for an upper GI double contrast GI study and is able to give informed consent. 2. Include any patient over 18 not classified to belonging to a vulnerable group. No upper age limit

Exclusion criteria

Exclusion criteria: 1. Aged below 18 years of age. 2. Unable to give consent 3. Member of vulnerable group

Design outcomes

Primary

MeasureTime frame
1. Is the experimental soft drink used for gaseous distension of the upper GI tract not inferior to the gold standard Carbex against delta at study clinic? 2. Does the experimental soft drink provide a diagnostic upper GI double contrast barium study when used in the place of Carbex at study clinic?

Secondary

MeasureTime frame
1. If the soft drink effervescent agent is found to be noninferior then a superiority test will be performed to ascertain whether it is better than Carbex. 2. What are the potential cost savings of using the soft drink over Carbex within this institution and nationwide? Both assessed at the study clinic

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026