Cardiovascular Circulatory System
Conditions
Interventions
Plan of investigation
Morning study (8.30-11.00 a.m.) - Lower Body Negative Pressure (LBNP) studies.
Patient will be allocated to pacemaker ON or OFF (Investigators will be blinded to the pacemaker mo
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients will be identified from Professor Frenneaux?s Heart Failure clinic who have already had a biventricular pacemaker implanted for clinical reasons. These patients will be approached by Professor Frenneaux or a member of his Research team and informed of the study. If the patients are interested in taking part they will be sent a copy of the patient information sheet and a reply letter. If they agree to take part they will be contacted and recruited into the study. Inclusion criteria: 1. NYHA Class I-III heart failure 2. Implanted with a biventricular pacemaker in the preceding 12 months 3. Physically capable of performing a cycle exercise test
Exclusion criteria
Exclusion criteria: 1. NYHA Class IV heart failure 2. Terminal illness 3. Women of child-bearing potential 4. Women currently breast-feeding 5. Significant arthritis limiting ability to perform a cycle exercise test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed