Cardiovascular: Stroke Circulatory System Stroke
Conditions
Interventions
Interventions added as of 18/07/2007:
Patients will be randomised into control and intervention groups by randomly picking up envelopes with predetermined entry to either group. Controls receive rout
Sponsors
Norfolk and Norwich University Hospital (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Added 18/07/2007: Patients who are admitted within 24 hours of a presumed vascular stroke (either ischaemic or haemorrhagic) resulting in hospitalisation with significant motor disability (right /left hemiparesis) defined as power 3 out of 5 or less in at least one limb.
Exclusion criteria
Exclusion criteria: Added 18/07/2007: 1. History of Chronic Obstructive Pulmonary Disease (COPD) / asthma with a previous history of CO2 retention 2. Presence of acute illness which affects oxygen saturation / delivery or requires oxygen as part of routine management e.g. anaemia (Hb <10), Pulmonary Embolism (PE) or pneumonia 3. Patients whose stroke occurred as a result of condition other than cerebrovascular event (e.g. brain tumour) 4. Comatose patients with Glasgow Coma Scale (GCS) level < 10
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome measures: 1. Changes in pH at the end of experiment 2. Changes in pCO2 at the end of experiment 3. Changes in respiratory rate at the end of experiment Other relevant outcome measures: 1. Change in blood pressure 2. Change in pulse oximetry | — |
Secondary
| Measure | Time frame |
|---|---|
| Added 18/07/2007: No secondary outcome measures | — |
Countries
United Kingdom
Outcome results
None listed